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==News About Licorice== | ==News About Licorice== | ||
'''Liquorice slows skins cancer cells: Compound found in root could hold key to beating most lethal form of the disease''' | |||
*Source: http://www.dailymail.co.uk/health/article-2451589/Liquorice-slows-skins-cancer-cells-Compound-root-hold-key-beating-lethal-form-disease.html | |||
:By Pat Hagan (for MailOnline) | |||
• Breakthrough could lead to new drug to combat malignant melanoma | |||
Liquorice could hold the key to beating the most lethal form of skin cancer, scientists have discovered. | |||
Research carried out in the US has identified a compound found in liquorice root which slowed the growth of cancer cells during laboratory tests. | |||
Now they hope the tumour-busting compound can be developed into a new drug to combat malignant melanoma. | |||
Previous studies have found liquorice contains an anti-cancer chemical called glycyrrhizin. | |||
But attempts to turn it into a medicine have been hampered by the fact that long-term consumption of glycyrrhizin can cause high blood pressure and even swelling on the brain. | |||
But experts at the University of Minnesota in the US have now found another ingredient - called Isoangustone A - which has the same benefits but without the dangerous side-effects. | |||
Malignant melanoma kills around 1,700 people a year in the UK and is the third most common cancer in people aged 15 to 39. | |||
Over-exposure to the sun’s rays is the biggest cause and since the mid-1990s there has been a 24 per cent increase in cases. | |||
Some evidence suggests even a few early bouts of sunburn in childhood can be enough to trigger the cellular changes in moles that lead to skin cancer later in life. | |||
Cells within moles become cancerous and start to divide uncontrollably, eventually spreading through the body. | |||
Some evidence suggests even a few early bouts of sunburn in childhood can be enough to trigger the cellular changes in moles that lead to skin cancer later in life | |||
The disease has historically had a very high death rate as the cancer has often spread by the time patients seek help. | |||
Recently new drugs have emerged that appear to halt the spread of tumours by ‘resetting’ the immune system so that it is able to attack malignant cells. | |||
In the latest research, scientists extracted Isoangustone A from liquorice root and applied it to skin cancer cells in the laboratory. | |||
The compound slowed down the rate at which melanoma cells reproduce, partly by blocking the release of certain proteins needed for them to flourish. | |||
When the scientists gave the extract to mice with skin cancer, it had the same effect - suppressing growth of the tumour. | |||
Liquorice is already a popular remedy for cold sores. A balm made from the root can reduce the severity of outbreaks. | |||
But too much liquorice can be harmful. A Scottish study found children born to women who ate over 100 grammes a week during pregnancy performed worse in intelligence tests at school and the harmful compound glycyrrhizin was blamed. | |||
In a report on their findings, published in the journal Cancer Prevention Research, scientists said: ‘Liquorice root is known to possess anti-inflammatory and anti-cancer effects. | |||
We found Isoangustone A suppressed the proliferation of human melanoma cells and provides the basis for the potential development of a new agent.’ | |||
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'''Growing Licorice in Your Herb Garden''' | '''Growing Licorice in Your Herb Garden''' | ||
*Source:http://www.motherearthnews.com/organic-gardening/growing-licorice-in-your-herb-garden-zmaz82jazgoe | *Source:http://www.motherearthnews.com/organic-gardening/growing-licorice-in-your-herb-garden-zmaz82jazgoe | ||