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==News About Peppermint == | ==News About Peppermint == | ||
'''IBS: Peppermint Oil May Be a Treatment Option''' | |||
*Source:http://www.medpagetoday.com/meetingcoverage/ddw/51604 | |||
:By Ed Susman (Contributing Writer, MedPage Today) | |||
- Slow-release formula offers relief within an hour. | |||
WASHINGTON -- A slow-release peppermint oil (IBgard) appeared to significantly reduce severe abdominal symptoms of irritable bowel syndrome (IBS), researchers said here. | |||
At 28 days, the number of severe and unbearable symptoms was reduced by 66% among patients taking peppermint oil compared with a reduction of 42% among patients on placebo (P=0.0212), reported Brooks Cash, MD, of the University of South Alabama in Mobile, and colleagues. | |||
When patients with severe or unbearable abdominal pain took peppermint oil, they reported a 79.4% reduction in symptoms while placebo patients reported a 40.2% reduction in symptoms after 4 weeks of therapy (P<0.0009), they stated in a poster presentation at the Digestive Disease Week annual meeting. | |||
"I have begun to prescribe this peppermint oil formula for my patients with irritable bowel syndrome," Cash told MedPage Today. "We had no discontinuations in either the placebo or the active ingredient arm of the trial due to problems with the agents. In fact, we had some patients who, after completion of the trial, told me they wanted to continue the treatment. We had a lot of positive feedback from the patients." | |||
Cash said that, even after 24 hours treatment, treatment with peppermint oil began to show an impact in symptoms. There was a 21% reduction in symptoms with placebo and a 30% reduction in symptoms with peppermint oil (P=0.0910), he and colleagues reported. | |||
L-menthol, the main constituent of peppermint oil, has anti-spasmodic, anti-carminative, topical analgesic, anti-infective, and 5-HT3 receptor antagonism properties, the authors explained. | |||
IBgard is "a unique formulation of ultra-purified peppermint oil," they wrote. | |||
"The peppermint oil that you can buy over-the-counter comes typically as capsules or gel caps that are subject to unpredictable dosing delivery," Cash said. As a result, patients who have early release of peppermint oil can experience heartburn and dyspepsia, he explained, while patients who have later release can experience anal burning and lower gastrointestinal symptoms. | |||
"It's really the [IBgard] delivery system that is designed to get the peppermint oil out of the stomach and into the small intestine where it is PH-released and where, we believe, it is having its primary effect," he said. | |||
The group recruited 35 patients who were assigned to treatment with peppermint oil and 37 patients who were assigned to placebo. One patient in each arm withdrew from the study. All the patients were required to meet the Rome III criteria for IBS, and had to have an average daily score of 4 or greater on a 10-point scale, as well as a Total IBS Symptom Score of 2 or greater. | |||
The patient population had a mean age of about 40 and 80% were women. The majority were Caucasian. | |||
IBS symptoms that the patients rated as severe or unbearable included abdominal pain or discomfort, abdominal bloating, constipation, and passage of gas or mucus. | |||
Across the groups, the reduction in symptoms ranged from 30% to 50% at 1 hour, while the reduction in symptoms after 28 days ranged from 70% to 90%. | |||
"Peppermint oil [treatment] is not a new idea," Cash acknowledged. "The key here is to minimize those side effects that can occur with peppermint oil while taking advantage of the benefits." | |||
Syed Shah, PhD, a researcher at IM HealthScience in Boca Raton, Fla., told MedPage Today that the product is expected to be on pharmacy shelves in June. He said IBGard, which is an IM HealthScience product, will sell for about $30 for a package of 48 tablets. During the study, two tablets were taken 30 minutes to 90 minutes before a meal, three times a day. | |||
"Even though we didn't study it, I think patients will take the peppermint oil as needed," Cash said. "At this point we have no evidence that there is a carryover effect -- pain relief will be achieved after the medication is discontinued." | |||
In commenting on the study, John Wysocki, MD, a fellow in gastroenterology at Tulane University in New Orleans, told MedPage Today that "peppermint oil has been used for generations, even hundreds of years for various stomach problems, so the use of this product in irritable bowel syndrome is not surprising. That's why they give peppermint [candies] away in restaurants." | |||
"There haven't been great studies on it, but there is some kind of interplay between peppermint and discomfort after eating," he added. "It is helpful because it helps to relax things in the gut and lets digestive juices, air, etc., do what they need to do and calm down a stomach that might be uncomfortable." | |||
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'''10 Peppermint Oil Health Benefits That Will Shock You''' | '''10 Peppermint Oil Health Benefits That Will Shock You''' | ||
*Source:http://www.healthaim.com/10-peppermint-oil-health-benefits-will-shock/59502 | *Source:http://www.healthaim.com/10-peppermint-oil-health-benefits-will-shock/59502 | ||