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| There are around 127,000 Parkinson’s sufferers and 12 in 100,000 have Huntington’s - an inherited condition that damages nerve cells in the brain. | | There are around 127,000 Parkinson’s sufferers and 12 in 100,000 have Huntington’s - an inherited condition that damages nerve cells in the brain. |
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| Alzheimer's disease
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| Liquorice could be used to treat Alzheimer's and Parkinson's
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| 18:58, 1 Dec 2015
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| Updated 20:22, 1 Dec 2015
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| By Fiona Parker
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| Currently 850,000 people in the UK are living with Alzheimer’s, but this number is expected to soar to over one million by 2025
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| REX Shutterstock Licorice sweets
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| Delicious: Synthetic liquorice sweets
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| Liquorice root extract could be used to treat Alzheimer’s and other neurodegenerative diseases such as Parkinson’s and Huntington’s, a study revealed.
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| Salicylic acid, a bitter chemical found in some plants and a critical hormone for regulating plants’ immune systems , is also a component in aspirin.
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| It binds to the enzyme GAPDH, which is believed to play a role in neurodegenerative diseases stopping the enzyme moving into a cell’s nucleus where it can trigger its death.
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| But derivatives, such as from liquorice or synthesised versions, were even more effective than aspirin in stopping the enzyme.
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| Currently 850, 000 people in the UK are living with Alzheimer’s, but this number is expected to soar to over one million by 2025.
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| There are around 127,000 Parkinson’s sufferers and 12 in 100,000 have Huntington’s - an inherited condition that damages nerve cells in the brain.
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| Disease sufferers in UK
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| Alzheimer’sParkinson’s0100,000200,000300,000400,000500,000600,000700,000800,000900,000
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| The anti-Parkinson’s drug deprenyl also blocks GAPDH’s entry into the nucleus but the study suggests salicylic acid can achieve the same goal. | | The anti-Parkinson’s drug deprenyl also blocks GAPDH’s entry into the nucleus but the study suggests salicylic acid can achieve the same goal. |
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| The study was published in the journal PLOS ONE. | | The study was published in the journal PLOS ONE. |
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| '''Liquorice slows skins cancer cells: Compound found in root could hold key to beating most lethal form of the disease''' | | '''Liquorice slows skins cancer cells: Compound found in root could hold key to beating most lethal form of the disease''' |