Difference between revisions of "Ringworm Bush (Akapulko)"

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==News about Ringworm Bush (Akapulko)==
==News about Ringworm Bush (Akapulko)==
'''Atis, Akapulko and Kapal-kapal, plants with potential anti-cancer compounds'''
*Source:http://www.pchrd.dost.gov.ph/index.php/news/r-d-updates/3127-atis-akapulko-and-kapal-kapal-plants-with-potential-anti-cancer-compounds
:(PCHRD)
“In the management of cancer, there is chemotherapy which uses natural products or drugs that kill cancer cells. And in our study, we are trying to discover possible chemotherapeutic properties derived from plant sources,” said Dr. Sonia D. Jacinto, Anticancer Natural Products Professor of the University of the Philippines Diliman (UPD).
The research conducted by the group of Dr. Jacinto entitled “Philippine Plants Showing Cytotoxic Activity to Selected Human Cancer Cell Lines” aims to isolate the compounds that are responsible for the cancer-killing action of the plant extracts to enable development of anti-cancer drugs.
“We grow a lot of cancer cells and place the plant extracts in it to observe if the cancer cells can grow. If they grow, then the study is unsuccessful. If it dies, it is a good sign that we can proceed to the next stage,” explained Dr. Jacinto.
Among the interesting findings obtained from their study was from the plant Annona Squamosa, more commonly known as “Atis.” According to Dr. Jacinto, Annona Squamosa is a close relative of Annona Muricata or “Guyabano” which is rich in Murihexocin C, compound active as anti-cancer agent.
Another plant which showed potential was Akapulko (Cassia Alata). Akapulko is a herbal medicine that is known to have anti-microbial and anti-fungal properties. Dr. Jacinto’s group discovered that Akapulko also has cytotoxic activity against some cancer cell lines.
“We have isolated a mixture of polyunsaturated fatty acid esters. The isolate may have potential for development as cancer chemotherapeutic agents,” said Dr. Jacinto.
Dr. Jacinto’s group also discovered cytotoxicity or cell-killing properties from Calotropis Gigantea or “Kapal-kapal.” Results showed that the compounds were extremely toxic to the human cancer cell lines such as colon carcinoma, lung non-small cell adenocarcinoma and liver hepatocarcinoma.
Kapal-kapal is cultivated as an ornamental and medicinal plant in the Philippines. Based on Dr. Jacinto’s research, the leaves of the plant can be applied as a dry fomentation for abdominal pains. Ethanolic extract of Kapal-kapal roots has also shown significant inhibitory effects against chronic myelogenous leukemia and human gastric cancer cell lines.
According to Dr. Jacinto, there are still other plant species that can be studied further for their cancer-killing properties. Dr. Jacinto encouraged young researchers to conduct researches on medicinal plants to contribute in the treatment of cancer.
“This is the line of work that we do. You can perhaps do something like this. You can use this as a jump start of your researches,” said. Dr. Jacinto.
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'''It’s not too early for gardeners to dream of autumn blooms '''
'''It’s not too early for gardeners to dream of autumn blooms '''
*Source:http://www.theneworleansadvocate.com/features/13220683-171/its-not-too-early-for
*Source:http://www.theneworleansadvocate.com/features/13220683-171/its-not-too-early-for
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