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Difference between revisions of "Malunggay Moringa Oleifera"
Malunggay Moringa Oleifera (view source)
Revision as of 23:50, 29 September 2013
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Different concentrations of malunggay leaf extracts: 25%, 50%, 75% and 0% were prepared. These extracts were treated to three (3) mice each as treated to the four groups of mice. | Different concentrations of malunggay leaf extracts: 25%, 50%, 75% and 0% were prepared. These extracts were treated to three (3) mice each as treated to the four groups of mice. | ||
Data analysis revealed that there was a significant difference in the mean blood glucose level of white mice when subjected to various levels of malunggay leaves extract, the lower the blood glucose, The findings confirmed that the malunggay leaf extract has a hypoglycemic property that can be used as hypoglycemic drugs. Thus, it can be used in treating diabetes. | Data analysis revealed that there was a significant difference in the mean blood glucose level of white mice when subjected to various levels of malunggay leaves extract, the lower the blood glucose, The findings confirmed that the malunggay leaf extract has a hypoglycemic property that can be used as hypoglycemic drugs. Thus, it can be used in treating [[Herbal Remedies for Diabetes Mellitus|diabetes]]. | ||
*<font size=4>What other websites are saying about Malunggay Moringa Oleifera</font> | *<font size=4>What other websites are saying about Malunggay Moringa Oleifera</font> | ||
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==What The [http://www.ncbi.nlm.nih.gov/pubmed/22103446 US National Library of Medicine National Institutes of Health] says:== | ==What The [http://www.ncbi.nlm.nih.gov/pubmed/22103446 US National Library of Medicine National Institutes of Health] says:== | ||
Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental diabetes.<br> | Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental [[Herbal Remedies for Diabetes Mellitus|diabetes]].<br> | ||
Gupta R, Mathur M, Bajaj VK, Katariya P, Yadav S, Kamal R, Gupta RS.<br> | Gupta R, Mathur M, Bajaj VK, Katariya P, Yadav S, Kamal R, Gupta RS.<br> | ||
Source<br> | Source<br> | ||
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Diabetic rats were treated with 150 or 300 mg/kg MOMtE for 21 days and the antidiabetic effects of the extract were evaluated by measuring changes in biochemical parameters in the serum and pancreatic tissue. Two phytoconstituents, namely quercetin and kaempferol, were isolated from the MOMtE extract and their structures were determined using nuclear magnetic resonance and infrared spectroscopy. | Diabetic rats were treated with 150 or 300 mg/kg MOMtE for 21 days and the antidiabetic effects of the extract were evaluated by measuring changes in biochemical parameters in the serum and pancreatic tissue. Two phytoconstituents, namely quercetin and kaempferol, were isolated from the MOMtE extract and their structures were determined using nuclear magnetic resonance and infrared spectroscopy. | ||
RESULTS:<br> | RESULTS:<br> | ||
The progression of diabetes was significantly reduced after MOMtE treatment. In treated rats, both doses of MOMtE induced a significant reduction in serum glucose and nitric oxide, with concomitant increases in serum insulin and protein levels. Furthermore, MOMtE treatment increased antioxidant levels in pancreatic tissue, with concomitant decreases in levels of thiobarbituric acid-reactive substances. Histologic examination of the pancreas from diabetic rats showed degenerative changes in β-cells; MOMtE treatment significantly reversed the histoarchitectural damage to the islets cells. | The progression of [[Herbal Remedies for Diabetes Mellitus|diabetes]] was significantly reduced after MOMtE treatment. In treated rats, both doses of MOMtE induced a significant reduction in serum glucose and nitric oxide, with concomitant increases in serum insulin and protein levels. Furthermore, MOMtE treatment increased antioxidant levels in pancreatic tissue, with concomitant decreases in levels of thiobarbituric acid-reactive substances. Histologic examination of the pancreas from diabetic rats showed degenerative changes in β-cells; MOMtE treatment significantly reversed the histoarchitectural damage to the islets cells. | ||
CONCLUSION:<br> | CONCLUSION:<br> | ||
In conclusion, M. oleifera exerts protective effects against STZ-induced diabetes. The MOMtE exhibited significant antidiabetic and antioxidant activity and active constituents may be isolated from the extract for evaluation in future clinical studies. | In conclusion, M. oleifera exerts protective effects against STZ-induced [[Herbal Remedies for Diabetes Mellitus|diabetes]]. The MOMtE exhibited significant antidiabetic and antioxidant activity and active constituents may be isolated from the extract for evaluation in future clinical studies. | ||
© 2011 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd. | © 2011 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd. | ||