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The Philippines has Zambo Mart to help propagate the Chavacano Language.
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Chronic inflammation of the hair follicle (HF) is considered a contributing factor in the pathogenesis of androgenetic alopecia (AGA). (R. M. Trüeb, Experimental Gerontology, vol. 37, no. 8-9, pp. 981–990, 2002) | Chronic inflammation of the hair follicle (HF) is considered a contributing factor in the pathogenesis of androgenetic alopecia (AGA). (R. M. Trüeb, Experimental Gerontology, vol. 37, no. 8-9, pp. 981–990, 2002) | ||
Hirsutism | :Hirsutism | ||
Hirsutism is the presence of excess hair in women. This phenomenon is usually an androgen-dependent process. 25 to 35 per cent of young women have terminal hair over the lower abdomen, around the nipples, or over the upper lip. Most women gradually develop more androgen-dependent body hair with age. Nevertheless, normal patterns of female hair growth are unacceptable to many women. At the other extreme, severe hirsutism may rarely be the earliest signs of masculinising diseases. More often, however, severe hirsutism reflects only increased androgen production in women with a non serious underlying disorder. | |||
It’s often caused by genes, hormones, or medication. Sometimes, hirsutism runs in families. It’s also more common in people from the Middle East, South Asia, and the Mediterranean. Many times, the condition is linked to high levels of male hormones (called androgens). It’s normal for women’s bodies to make these, and low levels don’t cause excess hair growth. But when these amounts are too high, they can cause hirsutism and other things, like acne, a deep voice, and small breasts. High levels of male hormones and hirsutism are common in women who have Polycystic ovarian syndrome, Cushing’s syndrome etc. | It’s often caused by genes, hormones, or medication. Sometimes, hirsutism runs in families. It’s also more common in people from the Middle East, South Asia, and the Mediterranean. Many times, the condition is linked to high levels of male hormones (called androgens). It’s normal for women’s bodies to make these, and low levels don’t cause excess hair growth. But when these amounts are too high, they can cause hirsutism and other things, like acne, a deep voice, and small breasts. High levels of male hormones and hirsutism are common in women who have Polycystic ovarian syndrome, Cushing’s syndrome etc. | ||
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Saw palmetto extract: Studies have shown that Saw palmetto is an effective anti-androgen. It acts in a similar way that Finasteride does. Firstly it lowers levels of DHT in the body by blocking 5 alpha-reductase. Secondly, Saw palmetto blocks receptors sites on cell membranes required for cells to absorb DHT. Studies have been performed on the use of Saw palmetto in the treatment of benign prostatic disease, which is similar to androgenetic alopecia in that it also depends on the production of dihydrotestosterone. | Saw palmetto extract: Studies have shown that Saw palmetto is an effective anti-androgen. It acts in a similar way that Finasteride does. Firstly it lowers levels of DHT in the body by blocking 5 alpha-reductase. Secondly, Saw palmetto blocks receptors sites on cell membranes required for cells to absorb DHT. Studies have been performed on the use of Saw palmetto in the treatment of benign prostatic disease, which is similar to androgenetic alopecia in that it also depends on the production of dihydrotestosterone. | ||
What is Saw palmetto? | :What is Saw palmetto? | ||
Saw palmetto is an extract derived from the deep purple berries of the saw palmetto fan palm (Serenoa repens), a plant indigenous to the coastal regions of the southern United States and southern California. There is an estimated one million acres of wild saw palmetto palms in Florida, where the bulk of commercial saw palmetto is grown. | Saw palmetto is an extract derived from the deep purple berries of the saw palmetto fan palm (Serenoa repens), a plant indigenous to the coastal regions of the southern United States and southern California. There is an estimated one million acres of wild saw palmetto palms in Florida, where the bulk of commercial saw palmetto is grown. | ||
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Based on mechanisms of action, Saw palmetto extracts are also used for male pattern baldness (alopecia), excess hair in women (hirsutism), acne, inflammatory skin disorder (seborrhea) and eczema. | Based on mechanisms of action, Saw palmetto extracts are also used for male pattern baldness (alopecia), excess hair in women (hirsutism), acne, inflammatory skin disorder (seborrhea) and eczema. | ||
Mechanisms of action | :Mechanisms of action | ||
Anti-androgenic and anti-inflammatory activities: Saw palmetto extracts inhibit 5a-reductase, which is an enzyme responsible for conversion of testosterone to dihydrotestosterone. Inhibition of such conversion maintains prostate health. | Anti-androgenic and anti-inflammatory activities: Saw palmetto extracts inhibit 5a-reductase, which is an enzyme responsible for conversion of testosterone to dihydrotestosterone. Inhibition of such conversion maintains prostate health. | ||
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Hirsutism in women is also related to this enzyme. | Hirsutism in women is also related to this enzyme. | ||
Role of Saw palmetto | :Role of Saw palmetto | ||
Recently, a number of clinical trials have confirmed the effectiveness of saw palmetto in treating BPH. Many of these trials have shown saw palmetto works better than the most commonly used prescription drug, Finasteride. Saw palmetto is effective in nearly 90 per cent of patients after six weeks of use, while finasteride is effective in less than 50 per cent of patients. In addition, finasteride may take up to six months to achieve its full effect. Since finasteride blocks the production of testosterone, it can cause impotence and breast enlargement. Other prescription drugs used to treat BPH are doxazosin, terazosin, and tamsulosin hydrochloride. Originally prescribed to treat hypertension, doxazosin and terazosin can drop blood pressure, causing light headedness and fainting. Presently, saw palmetto is being evaluated by the US Food and Drug Administration (FDA) for treatment of BPH. If approved, it would become the first natural derived product to be licensed by the agency as a treatment for a specific condition. | Recently, a number of clinical trials have confirmed the effectiveness of saw palmetto in treating BPH. Many of these trials have shown saw palmetto works better than the most commonly used prescription drug, Finasteride. Saw palmetto is effective in nearly 90 per cent of patients after six weeks of use, while finasteride is effective in less than 50 per cent of patients. In addition, finasteride may take up to six months to achieve its full effect. Since finasteride blocks the production of testosterone, it can cause impotence and breast enlargement. Other prescription drugs used to treat BPH are doxazosin, terazosin, and tamsulosin hydrochloride. Originally prescribed to treat hypertension, doxazosin and terazosin can drop blood pressure, causing light headedness and fainting. Presently, saw palmetto is being evaluated by the US Food and Drug Administration (FDA) for treatment of BPH. If approved, it would become the first natural derived product to be licensed by the agency as a treatment for a specific condition. | ||
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Although initial research of saw palmetto for the treatment of acne is promising, Dr Richard Fried writes in the report ‘Saw palmetto as a Treatment for Acne’ that the effectiveness of saw palmetto for acne treatment varies from person to person. | Although initial research of saw palmetto for the treatment of acne is promising, Dr Richard Fried writes in the report ‘Saw palmetto as a Treatment for Acne’ that the effectiveness of saw palmetto for acne treatment varies from person to person. | ||
Conclusion | :Conclusion | ||
Saw palmetto is better known for its ability to help treat BPH in men; however, the primary active constituents within saw palmetto also help reduce the severity of acne. According to the University of Maryland Medical Center the primary constituents of saw palmetto include plant sterols, fatty acids and flavonoids. Saw palmetto contains a high concentration of polysaccharides, which are used by the human body to enhance the immune system as well as work as an anti-inflammatory. One of the primary benefits of saw palmetto is its ability to hinder the transformation of testosterone to dihydrotestosterone, which is also known as DHT. | Saw palmetto is better known for its ability to help treat BPH in men; however, the primary active constituents within saw palmetto also help reduce the severity of acne. According to the University of Maryland Medical Center the primary constituents of saw palmetto include plant sterols, fatty acids and flavonoids. Saw palmetto contains a high concentration of polysaccharides, which are used by the human body to enhance the immune system as well as work as an anti-inflammatory. One of the primary benefits of saw palmetto is its ability to hinder the transformation of testosterone to dihydrotestosterone, which is also known as DHT. |
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